The 1st Battalion left Southampton in the Nubia on 22 October and arrived in Cape Town just over three weeks later.   Along with the 3rd Grenadier Guards and 1st and 2nd Coldstream Guards they formed the Guards Brigade under Sir H E Colvile. The 2nd Battalion sailed on the Britannic on 15th March 1900, and arrived at the Cape on 5th April. Along with the 2nd Grenadiers, 2nd East Yorkshire, and 1st Leinster Regiment, they formed the 16th Brigade under Major General Barrington Campbell, and part of the V111th Division under General Sir Leslie Rundle.

The names of the men who served in the regiment are listed below